lipid nanoparticle, lipid nanoparticles, Lipid NP, LNP, LNP preparation, LNP formulation, lipid nanoparticle synthesis, liposome, mRNA encapsulation, precigenome, mRNA LNP, PLGA, drug delivery, precision medicine, nanogenerator, flex-s, flex-m, pro, max, precisionnanosystems, pni, NanoAssemblr, ignite, spark

液滴生成系统with 微流控液滴发生器芯片

droplet generation, droplet generator, microhigh_speed_imaging_flow_controller, droplet generation, droplet generator, microfluidic droplet, droplet generation chip, droplet generator chip, microfluidic pump, microfluidic pressure pump, microfluidic pressure controller, microfluidic, high-speed imaging

微粒，尤其是聚合物微粒，以其优异的性能在药物输送、生物传感等制药工业等各个领域显示出巨大的生物医学应用潜力。

通过微流控技术合成微粒比传统的批量合成工艺具有优势，因为它能够在尺寸和形状上具有更好的均匀性。例如，在药物输送领域，纳米粒子可以由嵌段共聚物合成，例如 PLGA，这是最常用的生物可降解材料，用于输送亲水性和疏水性化合物。

粒子合成原理：

PreciGenome 液滴生成系统广泛用于微粒合成。它采用微流体装置来控制和调节聚合物颗粒的生产。下面的示意图说明了为粒子合成而设计的具有聚焦流几何结构结的设备。

微粒合成：

扩大的连接处的示意图，孔口处受控的破碎液滴。通过孔口的流动能够控制液滴破碎，这是产生单分散微乳液所必需的

系统优势：

High Performance & Efficiency

Tunable size
Low PDI
High encapsulation efficiency

Total Solution

Dedicated protocol
Technical support
Including everything you need
- Instrument and chips
- Highspeed Imaging

Cost Effective

Affordable configurations
Cost effective solutions
Open platform

Custom Design & Service

Research collaboration
Custom design
OEM & Contract manufacturing

high_speed_imaging_flow_controller, microparticle system, nanoparticle synthesis, microfluidic mixing, high-speed imaging,drug delivery, PLGA synthesis, lipid synthesis, liposome synthesis

微流控方法的优点：

The iFlow system offers a variety of numerous benefits by using microfluidic systems to produce PLGA mircoparticles for drug delivery applications, such as:

Enhanced control of particle fabrication process over each phase
High yields
Easy scale-up

In drug delivery, precise particle production is essential for controlled and sustained release of drugs using biodegradable polymers. The iFlow systems offer advantages like enhanced control over particle production, higher yields, and easy scale-up. Targeted drug delivery is also possible by functionalizing particle surfaces or using the EPR effect. The release profiles of the polymer-drug matrix can be adjusted by varying factors like microparticle size, polymer molecular weight, lactide to glycolide ratio, and drug concentration.

相关应用说明：

PLGA Nanoparticle Synthesis

Drug-loaded PLGA nanoparticles (NPs) can be synthesized by our system. PLGA NPs synthesis in continuous flow microfluidics by the nanoprecipitation process.

Liposome Nanoparticle Synthesis

Precise lipid and liposome synthesis by microfluidic mixing methods. Efficient method for generating nanoparticles for targeted drug or nutrient delivery