LipidFlex™ 脂质纳米颗粒和脂质体制剂
LipidFlex™ 是一种三组分脂质混合物。
LipidFlex™ 可直接用于生成用于小分子封装的脂质体。除了不同的阳离子/可电离脂质，LipidFlex™ 还可用于生成脂质纳米颗粒 (LNP)，用于封装小分子和核酸，如 mRNA、DNA、蛋白质等。
LipidFlex™ Pack 套件包括 LipidFlex 和可电离脂质 (SM102)
Benefits of RNA-LNP Products
Enhanced delivery
Facilitate more efficient uptake of RNA by cells, leading to higher levels of protein expression.
High encapsulation efficiency
Encapsulation Efficiency (E.E.%): >80% (>95-99% w. optimized conditions)
Reduced immunogenicity
Improve the safety and efficacy of RNA-based therapies and vaccines.
High stability
Protect RNA from degradation by enzymes and other factors, allowing for improved delivery of the RNA to the target cells.
实验数据：
GFP expression in K562 (left) and HepG2 (right) cell lines after48 hours treated by eGFP mRNA-LNP
Accelerate your LNP Formulation Development
In Vitro
Evaluation
Quickly screen LNP formulations for cellular uptake and viability
In Vivo
Distribution
Understand the localization of your payloads complex
Scale-up and Optimization
Leverage insights & our expertise to refine LNP formulations for scale-up studies
Custom LNP
In addition to our off-the-shelf mRNA-LNP products, we proudly offer tailored customization services designed to meet the unique needs of your research and development projects. Our custom mRNA-LNP service is ideal for researchers and developers who require specific mRNA sequences or specialized formulations to achieve optimal results in their applications.
At PreciGenome, we understand that every project is distinct, with its own set of challenges and objectives. Whether you are working on vaccine development, gene therapy, or any other innovative application, our team is committed to delivering high-quality, bespoke mRNA-LNP formulations that align with your specific goals. Our customization process allows you to choose from a variety of mRNA sequences and lipid nanoparticle compositions, ensuring that your product is perfectly suited to your experimental needs.
Our state-of-the-art facilities and expert team ensure that each custom mRNA-LNP product is manufactured to the highest standards of quality and efficacy. Partner with PreciGenome to leverage our expertise and enhance the success of your research endeavors. Explore the possibilities with our custom mRNA-LNP services today, and let us help you push the boundaries of scientific discovery.
特征：
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In vitro or in vivo expression and distribution
Evaluate delivery of mRNA ( eGFP, FLuc, mCherry, etc.) for in vitro transfection
Evaluate LNP uptake with conveniently labeled lipophilic dyes
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Analytical or process development
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Experimental control reference
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