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lipid nanoparticle, lipid nanoparticles, Lipid NP,  LNP, LNP preparation, LNP formulation, lipid nanoparticle synthesis, liposome, mRNA encapsulation,   precigenome, mRNA LNP, PLGA, drug delivery, precision medicine, nanogenerator, flex-s, flex-m, pro, max, precisionnanosystems, pni, NanoAssemblr, ignite, spark
Lipid nanoparticle LNP, icon, precigenome
lipid nanoparticle, lipid nanoparticles, Lipid NP,  LNP, LNP preparation, LNP formulation, lipid nanoparticle synthesis, liposome, mRNA encapsulation,   precigenome, mRNA LNP, PLGA, drug delivery, precision medicine, nanogenerator, flex-s, flex-m, pro, max, precisionnanosystems, pni, NanoAssemblr, ignite, spark

High throughput 1-4 samples per run
Small volume output down to 50uL with optimized recipe

纳米发电机纳米粒子合成系统

PreciGenome NanoGenerator™ 是用于纳米粒子合成的高性能仪器,如脂质纳米粒子、脂质体、PLGA 等,广泛用于药物输送、基因治疗、LNP 配制和制造等。

NanoGenerator™ 生成的纳米粒子具有更好的尺寸均匀性和更小的 PDI。它可从 0.1mL/样品筛选扩展到 1L(>10L 定制设计)大批量 GMP 生产

纳米粒子,尤其是脂质体和聚合物纳米粒子,由于其优异的性能,在药物递送、mRNA疫苗和生物传感等制药工业等各个领域显示出巨大的生物医学应用潜力。

 
通过微流控技术合成纳米颗粒比传统的批量合成工艺具有优势,因为它能够在尺寸和形状上具有更好的均匀性。例如,在药物递送领域,使用NanoGenerator™纳米粒子合成系统可以合成脂质纳米粒子(LNP)、脂质体、PLGA等多种纳米粒子。脂质纳米颗粒 (LNP)、脂质体和 PLGA  是最常用的可生物降解材料,用于输送亲水性和疏水性化合物。 
Workflow
Flex-S introduction
lipid nanoparticle, lipid nanoparticles, Lipid NP,  LNP, LNP preparation, LNP formulation, lipid nanoparticle synthesis, liposome, mRNA encapsulation,   precigenome, mRNA LNP, PLGA, drug delivery, precision medicine, nanogenerator, flex-s, flex-m, pro, max, precisionnanosystems, pni, NanoAssemblr, ignite, spark

微流控混合器芯片:

PreciGenome 提供各种不同材料的微流控芯片,以满足我们大多数客户对纳米粒子合成的应用需求。
 
微流控混合器芯片通常用于纳米粒子合成。 三种类型的材料,包括聚合物、玻璃和硅,通常用于制造微流控芯片。芯片材料的选择取决于应用需求,包括芯片设计、实验所用溶剂或试剂的种类、应用需求、预算、制造时间等。 
lipid nanoparticle, lipid nanoparticles, Lipid NP,  LNP, LNP preparation, LNP formulation, lipid nanoparticle synthesis, liposome, mRNA encapsulation,   precigenome, mRNA LNP, PLGA, drug delivery, precision medicine, nanogenerator, flex-s, flex-m, pro, max, precisionnanosystems, pni, NanoAssemblr, ignite, spark
lipid nanoparticle, lipid nanoparticles, Lipid NP,  LNP, LNP preparation, LNP formulation, lipid nanoparticle synthesis, liposome, mRNA encapsulation,   precigenome, mRNA LNP, PLGA, drug delivery, precision medicine, nanogenerator, flex-s, flex-m, pro, max, precisionnanosystems, pni, NanoAssemblr, ignite, spark
System Specs

微流控混合器芯片:

lipid nanoparticle, lipid nanoparticles, Lipid NP,  LNP, LNP preparation, LNP formulation, lipid nanoparticle synthesis, liposome, mRNA encapsulation,   precigenome, mRNA LNP, PLGA, drug delivery, precision medicine, nanogenerator, flex-s, flex-m, pro, max, precisionnanosystems, pni, NanoAssemblr, ignite, spark

System Specifications

lipid nanoparticle, lipid nanoparticles, Lipid NP,  LNP, LNP preparation, LNP formulation, lipid nanoparticle synthesis, liposome, mRNA encapsulation,   precigenome, mRNA LNP, PLGA, drug delivery, precision medicine, nanogenerator, flex-s, flex-m, pro, max, precisionnanosystems, pni, NanoAssemblr, ignite, spark
Working Principle

有效载荷:

rna

mRNA/siRNA

peptide

Proteins and peptides

dna

DNA

small molecule

Small molecules

Payloads

 系统优势:​

  • 粒径可控

  • 低 DPI

  • 封装效率高

  • 标准连接。轻松连接到其他组件

  • 贴牌服务和模块集成可用

lipid nanoparticle, lipid nanoparticles, Lipid NP,  LNP, LNP preparation, LNP formulation, lipid nanoparticle synthesis, liposome, mRNA encapsulation,   precigenome, mRNA LNP, PLGA, drug delivery, precision medicine, nanogenerator, flex-s, flex-m, pro, max, precisionnanosystems, pni, NanoAssemblr, ignite, spark

演示视频和网络研讨会:

纳米发电机Flex-M演示视频 

纳米发电机ProMab Biotechnologies 的 LNP 合成与应用网络研讨会

Document & Inquiry

应用注意事项:

Application Notes

Application

Use case 3.gif

Lipid nanoparticle applications and technical notes

Publications

Article

Slide 4 LNP liposome comparison.PNG

Lipid nanoparticle publications 

Articles

Application

plga nanogenerator pro.png

Articles related the Lipid nanoparticles 

Related Products

我们的一些客户

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